Microsoft Mouse and Keyboard Centre software provides default commands for all of the mouse buttons. You can reassign some buttons to different commands or keyboard shortcuts to better fit your work style. You can also disable buttons you might press accidentally, such as the wheel button.
You can assign mouse buttons to perform different commands in different programs. For example, you can assign the same mouse button to activate Digital Ink when in PowerPoint, a macro when in a game, and the Magnifier when in any other application.
If you open a program by using the Run as administrator command, you will not have access to application-specific mouse button settings. Instead, the mouse will use the global mouse button assignments. To enable application-specific mouse button settings, open the application without administrator credentials, or log on to Windows as an administrator.