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Drive into downtown Cologne and follow the B9/B51 (north-south) along the river Rhine until you reach Holzmarkt. If you're northbound, you'll pass the Microsoft building right before the B51 is crossed by the Severinsbrücke. Park right at the art'otel's public parking lot. From there, it's a two minute walk back to Microsoft building ("Südturm"). If you're southbound, you'll need to make a U turn first at the first opportunity, and then continue on northbound as described previously.