Granting or Denying Access to a Domain (IIS 6.0)
Use the following procedure to grant or deny access to a specific domain.
You must be a member of the Administrators group on the local computer to perform the following procedure or procedures. As a security best practice, log on to your computer by using an account that is not in the Administrators group, and then use the runas command to run IIS Manager as an administrator. At a command prompt, type runas /user:Administrative_AccountName "mmc %systemroot%\system32\inetsrv\iis.msc".
To grant or deny access to a domain
Configuration settings made at the Web or FTP Sites level are inherited by all of the Web or FTP sites on the server. You can override inheritance by configuring the individual site or site element.