Married for five months, Jamie (Helen Hunt) and Paul Buchman (Paul Reiser) struggle to establish the ground rules of their life together in a Manhattan apartment. Paul, a documentary filmmaker, is charming and creative, but also cautious and analytical. Jamie, on the other hand, tends to be more of a free spirit. But as a public relations executive fighting her way up the corporate ladder, she has her own share of anxieties. Among those sharing Jamie and Paul's life are Jamie's luckless sister, Lisa (Anne Ramsay), Paul's handsome bachelor buddy Jay Selby (Tommy Hinkley), and their friends Dr. Mark Devanow (Richard Kind) and his wife Fran (Leila Kenzle). With honesty, charm and humor, Mad About You holds up a mirror to married life, to see what the world is like behind closed doors.