While code cloning is a convenient way for developers to reuse existing code, it could potentially lead to negative impacts, such as degrading code quality or increasing maintenance costs. Actually, some cloned code pieces are viewed as harmless since they evolve independently, while other cloned code pieces are viewed as harmful since they need to be changed consistently, thus incurring extra maintenance costs. Recent studies demonstrate that neither the percentage of harmful code clones nor that of harmless code clones is negligible. To assist developers in leveraging the beneﬁts of harmless code cloning and/or in avoiding the negative impacts of harmful code cloning, we propose a novel approach that automatically predicts the harmfulness of a code cloning operation at the point of performing copy-and-paste. Our insight is that the potential harmfulness of a code cloning operation may relate to some characteristics of the code to be cloned and the characteristics of its context. Based on a number of features extracted from the cloned code and the context of the code cloning operation, we use Bayesian Networks, a machine-learning technique, to predict the harmfulness of an intended code cloning operation. We evaluated our approach on two large-scale industrial software projects under two usage scenarios: 1) approving only cloning operations predicted to be very likely of no harm, and 2) blocking only cloning operations predicted to be very likely of harm. In the ﬁrst scenario, our approach is able to approve more than 50% cloning operations with a precision higher than 94.9% in both subjects. In the second scenario, our approach is able to avoid more than 48% of the harmful cloning operations by blocking only 15% of the cloning operations for the ﬁrst subject, and avoid more than 67% of the cloning operations by blocking only 34% of the cloning operations for the second subject.