{"id":235325,"date":"2016-05-29T09:04:08","date_gmt":"2016-05-29T16:04:08","guid":{"rendered":"https:\/\/www.microsoft.com\/en-us\/research\/?post_type=msr-project&#038;p=235325"},"modified":"2017-03-13T11:27:21","modified_gmt":"2017-03-13T18:27:21","slug":"hiv","status":"publish","type":"msr-project","link":"https:\/\/www.microsoft.com\/en-us\/research\/project\/hiv\/","title":{"rendered":"HIV Vaccine Design"},"content":{"rendered":"<p>HIV is one of the world&#8217;s primary health concerns.\u00a0 Researchers at Microsoft are collaborating with leading HIV scientific centers to bring together research expertise and cutting-edge computing technology in to the fight against the virus.\u00a0 Computational tools are available <a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"https:\/\/phylod.research.microsoft.com\/\">here<span class=\"sr-only\"> (opens in new tab)<\/span><\/a>.<\/p>\n<p><strong>In the news<\/strong><\/p>\n<p><a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"https:\/\/www.washingtonpost.com\/news\/to-your-health\/wp\/2016\/03\/04\/microsoft-research-scientist-david-heckerman-on-how-we-could-attack-hiv-like-spam\/\">Washington Post, 2016<span class=\"sr-only\"> (opens in new tab)<\/span><\/a><\/p>\n<p><a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"http:\/\/www.geekwire.com\/2013\/geek-week-david-heckerman\/\">Geek Wire, 2013<span class=\"sr-only\"> (opens in new tab)<\/span><\/a><\/p>\n<p><a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"http:\/\/www.fastcompany.com\/1842447\/microsoft-virus-fighter-spam-may-be-more-difficult-stop-hiv\">Fast Company, 2012<span class=\"sr-only\"> (opens in new tab)<\/span><\/a><\/p>\n<p><a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"https:\/\/blogs.msdn.microsoft.com\/msr_er\/2011\/08\/04\/understanding-the-immune-response-to-hiv\/\">Microsoft Blog, 2011<span class=\"sr-only\"> (opens in new tab)<\/span><\/a><\/p>\n<p><strong>Selected references<\/strong><\/p>\n<p>F. Pereyra, D. Heckerman, J. Carlson, C. Kadie, D. Soghoian, D. Karel, A. Goldenthal, O. Davis, C. DeZiel, T. Lin, J. Peng, A. Piechocka, M. Carrington, and B. Walker. <a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"http:\/\/jvi.asm.org\/content\/88\/22\/12937.long\">HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes<span class=\"sr-only\"> (opens in new tab)<\/span><\/a>. <em>J. Virol<\/em> 88 12937-12948, Aug 2014.<\/p>\n<p>J. Carlson, M. Schaefer, D. Monaco, R. Batorsky, D. Claiborne, J. Prince, M. Deymier, Z. Ende, N. Klatt, C. DeZiel, Tien-Ho Lin, J. Peng, A. Seese, R. Shapiro, J. Frater, T. Ndung\u2019u, J. Tang, P. Goepfert, J. Gilmour, M. Price, W. Kilembe, D. Heckerman, P. Goulder, T. Allen, S. Allen, and E. Hunter. <a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"http:\/\/www.sciencemag.org\/content\/345\/6193\/1254031\">Selection bias at the heterosexual HIV-1 transmission bottleneck<span class=\"sr-only\"> (opens in new tab)<\/span><\/a>. <em>Science<\/em>, 345(6193): 1254031, July 2014 (doi:10.1126\/science.1254031).<\/p>\n<p>R. Rubsamen, C. Herst, P. Lloyd, D. Heckerman. <a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0264410X14007579\">Eliciting cytotoxic T-lymphocyte responses from synthetic vectors containing one or two epitopes in a C57BL\/6 mouse model using peptide-containing biodegradable microspheres and adjuvants<span class=\"sr-only\"> (opens in new tab)<\/span><\/a>. <em>Vaccine<\/em> 32, 4111-4116, June 2014.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>HIV is one of the world&#8217;s primary health concerns.\u00a0 Researchers at Microsoft are collaborating with leading HIV scientific centers to bring together research expertise and cutting-edge computing technology in to the fight against the virus.\u00a0 Computational tools are available here. In the news Washington Post, 2016 Geek Wire, 2013 Fast Company, 2012 Microsoft Blog, 2011 [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":false,"_classifai_error":"","footnotes":""},"research-area":[13556,13553],"msr-locale":[268875],"msr-impact-theme":[],"msr-pillar":[],"class_list":["post-235325","msr-project","type-msr-project","status-publish","hentry","msr-research-area-artificial-intelligence","msr-research-area-medical-health-genomics","msr-locale-en_us","msr-archive-status-active"],"msr_project_start":"","related-publications":[],"related-downloads":[],"related-videos":[],"related-groups":[],"related-events":[],"related-opportunities":[],"related-posts":[],"related-articles":[],"tab-content":[],"slides":[],"related-researchers":[{"type":"user_nicename","value":"heckerma","display_name":"David Heckerman","author_link":"<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/people\/heckerma\/\" aria-label=\"Visit the profile page for David Heckerman\">David Heckerman<\/a>","is_active":false,"user_id":31991,"last_first":"Heckerman, David","people_section":0,"alias":"heckerma"}],"msr_research_lab":[],"msr_impact_theme":[],"_links":{"self":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project\/235325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project"}],"about":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/types\/msr-project"}],"version-history":[{"count":1,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project\/235325\/revisions"}],"predecessor-version":[{"id":365387,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project\/235325\/revisions\/365387"}],"wp:attachment":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/media?parent=235325"}],"wp:term":[{"taxonomy":"msr-research-area","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/research-area?post=235325"},{"taxonomy":"msr-locale","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-locale?post=235325"},{"taxonomy":"msr-impact-theme","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-impact-theme?post=235325"},{"taxonomy":"msr-pillar","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-pillar?post=235325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}