{"id":238001,"date":"2012-06-13T05:28:19","date_gmt":"2012-06-13T12:28:19","guid":{"rendered":"https:\/\/www.microsoft.com\/en-us\/research\/?post_type=msr-project&#038;p=238001"},"modified":"2017-06-21T08:44:33","modified_gmt":"2017-06-21T15:44:33","slug":"whole-organism-model-c-elegans-development","status":"publish","type":"msr-project","link":"https:\/\/www.microsoft.com\/en-us\/research\/project\/whole-organism-model-c-elegans-development\/","title":{"rendered":"Whole-Organism Model of C. Elegans Development"},"content":{"rendered":"<p>The nematode <i>C. elegans<\/i>, with its invariant lineage, serves as a model organism for the study of development. We aim to create an open-source, extensible whole-organism model of <i>C. elegans <\/i>development to which the worm community can add new information. In the first stage of this project we use this simulation program to study developmental variance in <i>C. elegans<\/i>, and in particular how this may arise through perturbations in cell-cycle timing. This early version of the model is used to provide new insights into embryogenesis under environmental stress, and into cell signalling through cell-cycle timing constraints.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The nematode C. elegans, with its invariant lineage, serves as a model organism for the study of development. We aim to create an open-source, extensible whole-organism model of C. elegans development to which the worm community can add new information. In the first stage of this project we use this simulation program to study developmental [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":false,"_classifai_error":"","footnotes":""},"research-area":[13553],"msr-locale":[268875],"msr-impact-theme":[],"msr-pillar":[],"class_list":["post-238001","msr-project","type-msr-project","status-publish","hentry","msr-research-area-medical-health-genomics","msr-locale-en_us","msr-archive-status-active"],"msr_project_start":"2013-01-06","related-publications":[],"related-downloads":[],"related-videos":[],"related-groups":[],"related-events":[],"related-opportunities":[],"related-posts":[],"related-articles":[],"tab-content":[],"slides":[],"related-researchers":[],"msr_research_lab":[],"msr_impact_theme":[],"_links":{"self":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project\/238001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project"}],"about":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/types\/msr-project"}],"version-history":[{"count":2,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project\/238001\/revisions"}],"predecessor-version":[{"id":392381,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-project\/238001\/revisions\/392381"}],"wp:attachment":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/media?parent=238001"}],"wp:term":[{"taxonomy":"msr-research-area","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/research-area?post=238001"},{"taxonomy":"msr-locale","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-locale?post=238001"},{"taxonomy":"msr-impact-theme","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-impact-theme?post=238001"},{"taxonomy":"msr-pillar","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-pillar?post=238001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}