{"id":861198,"date":"2022-07-12T02:43:53","date_gmt":"2022-07-12T09:43:53","guid":{"rendered":"https:\/\/www.microsoft.com\/en-us\/research\/"},"modified":"2023-02-13T11:29:13","modified_gmt":"2023-02-13T19:29:13","slug":"association-of-covid19-induced-anosmia-and-ageusia-with-depression-and-suicidal-ideation","status":"publish","type":"msr-research-item","link":"https:\/\/www.microsoft.com\/en-us\/research\/publication\/association-of-covid19-induced-anosmia-and-ageusia-with-depression-and-suicidal-ideation\/","title":{"rendered":"Association of COVID19-induced anosmia and ageusia with depression and suicidal ideation"},"content":{"rendered":"
\n

Background<\/h3>\n

Clinical reports from patients suffering from the novel coronavirus (COVID-19) reflect a high prevalence of sensory deprivation or loss pertaining to smell (dysosmia\/anosmia) and\/or taste (dysgeusia\/ageusia). Given the importance of the senses to daily functioning and personal experience, the mental health consequences of these symptoms warrant further attention.<\/p>\n<\/div>\n

\n

Methods<\/h3>\n

A cohort of Reddit users posting within the \/r\/covid19positive subforum (N<\/em>\u00a0=\u00a015,821) was leveraged to analyze instantaneous risk of transition to a state of\u00a0suicidal ideation<\/a>\u00a0or depression using Cox proportional-hazards models. Risk transition was defined by posts made in suicide- or depression-related forums, or mentions of relevant phrases with and without mention of anosmia\/ageusia in \/r\/covid19positive. Self-diagnosis of COVID-19 was also modeled as a separate and simultaneous predictor of mental health risk.<\/p>\n<\/div>\n

\n

Results<\/h3>\n

Mention of anosmia\/ageusia was significantly associated with transition to a risk state. Users with a history of anosmia\/ageusia-related posts and who self-identified as COVID-19 positive had 30% higher instantaneous risk relative to others. The highest increase in instantaneous risk of suicidal ideation or depression occurred more than 100 days after first posting in \/r\/covid19positive.<\/p>\n<\/div>\n

\n

Limitations<\/h3>\n

Use of self-diagnosed disease as well as a broad array of anosmia\/ageusia-related terminology may entail both information bias and overestimates of symptom incidence.<\/p>\n<\/div>\n

\n

Conclusions<\/h3>\n

The specific effects of COVID-19 on the senses may have long-term implications for patient mental health well-being beyond the primary recovery period. Future work is needed to investigate the longitudinal mental health burden of residual COVID-19 symptom presentation.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Background Clinical reports from patients suffering from the novel coronavirus (COVID-19) reflect a high prevalence of sensory deprivation or loss pertaining to smell (dysosmia\/anosmia) and\/or taste (dysgeusia\/ageusia). Given the importance of the senses to daily functioning and personal experience, the mental health consequences of these symptoms warrant further attention. Methods A cohort of Reddit users […]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":false,"_classifai_error":"","msr-author-ordering":null,"msr_publishername":"","msr_publisher_other":"","msr_booktitle":"","msr_chapter":"","msr_edition":"","msr_editors":"","msr_how_published":"","msr_isbn":"","msr_issue":"","msr_journal":"Journal of Affective Disorders Reports","msr_number":"","msr_organization":"","msr_pages_string":"","msr_page_range_start":"","msr_page_range_end":"","msr_series":"","msr_volume":"","msr_copyright":"","msr_conference_name":"","msr_doi":"","msr_arxiv_id":"","msr_s2_paper_id":"","msr_mag_id":"","msr_pubmed_id":"","msr_other_authors":"","msr_other_contributors":"","msr_speaker":"","msr_award":"","msr_affiliation":"","msr_institution":"","msr_host":"","msr_version":"","msr_duration":"","msr_original_fields_of_study":"","msr_release_tracker_id":"","msr_s2_match_type":"","msr_citation_count_updated":"","msr_published_date":"2021-7-1","msr_highlight_text":"","msr_notes":"","msr_longbiography":"","msr_publicationurl":"","msr_external_url":"","msr_secondary_video_url":"","msr_conference_url":"","msr_journal_url":"","msr_s2_pdf_url":"","msr_year":0,"msr_citation_count":0,"msr_influential_citations":0,"msr_reference_count":0,"msr_s2_match_confidence":0,"msr_microsoftintellectualproperty":true,"msr_s2_open_access":false,"msr_s2_author_ids":[],"msr_pub_ids":[],"msr_hide_image_in_river":0,"footnotes":""},"msr-research-highlight":[],"research-area":[13556,13553],"msr-publication-type":[193715],"msr-publisher":[],"msr-focus-area":[],"msr-locale":[268875],"msr-post-option":[],"msr-field-of-study":[],"msr-conference":[],"msr-journal":[],"msr-impact-theme":[],"msr-pillar":[],"class_list":["post-861198","msr-research-item","type-msr-research-item","status-publish","hentry","msr-research-area-artificial-intelligence","msr-research-area-medical-health-genomics","msr-locale-en_us"],"msr_publishername":"","msr_edition":"","msr_affiliation":"","msr_published_date":"2021-7-1","msr_host":"","msr_duration":"","msr_version":"","msr_speaker":"","msr_other_contributors":"","msr_booktitle":"","msr_pages_string":"","msr_chapter":"","msr_isbn":"","msr_journal":"Journal of Affective Disorders Reports","msr_volume":"","msr_number":"","msr_editors":"","msr_series":"","msr_issue":"","msr_organization":"","msr_how_published":"","msr_notes":"","msr_highlight_text":"","msr_release_tracker_id":"","msr_original_fields_of_study":"","msr_download_urls":"","msr_external_url":"","msr_secondary_video_url":"","msr_longbiography":"","msr_microsoftintellectualproperty":1,"msr_main_download":"","msr_publicationurl":"","msr_doi":"","msr_publication_uploader":[{"type":"url","viewUrl":"false","id":"false","title":"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666915321000822","label_id":"243109","label":0}],"msr_related_uploader":"","msr_citation_count":0,"msr_citation_count_updated":"","msr_s2_paper_id":"","msr_influential_citations":0,"msr_reference_count":0,"msr_arxiv_id":"","msr_s2_author_ids":[],"msr_s2_open_access":false,"msr_s2_pdf_url":null,"msr_attachments":[],"msr-author-ordering":[{"type":"user_nicename","value":"Elad Yom-Tov","user_id":31729,"rest_url":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/microsoft-research\/v1\/researchers?person=Elad Yom-Tov"},{"type":"text","value":"DamienLekkas","user_id":0,"rest_url":false},{"type":"text","value":"Nicholas C.Jacobson","user_id":0,"rest_url":false}],"msr_impact_theme":[],"msr_research_lab":[199563],"msr_event":[],"msr_group":[916890],"msr_project":[375953],"publication":[],"video":[],"msr-tool":[],"msr_publication_type":"article","related_content":{"projects":[{"ID":375953,"post_title":"Internet-Mediated Health","post_name":"internet-mediated-health","post_type":"msr-project","post_date":"2012-08-01 05:15:47","post_modified":"2022-07-14 02:17:04","post_status":"publish","permalink":"https:\/\/www.microsoft.com\/en-us\/research\/project\/internet-mediated-health\/","post_excerpt":"The majority of Internet users turn to the web for information when they have a medical concern. 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