{"id":1120251,"date":"2025-01-17T01:43:13","date_gmt":"2025-01-17T09:43:13","guid":{"rendered":"https:\/\/www.microsoft.com\/en-us\/research\/?post_type=msr-story&#038;p=1120251"},"modified":"2025-01-21T08:07:48","modified_gmt":"2025-01-21T16:07:48","slug":"wef_science","status":"publish","type":"msr-story","link":"https:\/\/www.microsoft.com\/en-us\/research\/story\/wef_science\/","title":{"rendered":"Microsoft at WEF"},"content":{"rendered":"\n<div class=\"wp-block-cover has-parallax is-style-default\" style=\"min-height:398px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-black-background-color has-background-dim-40 has-background-dim\"><\/span><div class=\"wp-block-cover__image-background wp-image-1122372 has-parallax\" style=\"background-position:50% 50%;background-image:url(https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/webpage_header_wef_1920x720_v4.png)\"><\/div><div class=\"wp-block-cover__inner-container is-layout-constrained wp-container-core-cover-is-layout-2cb6a229 wp-block-cover-is-layout-constrained\">\n<div class=\"wp-block-group is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-719fd2c2 wp-block-group-is-layout-constrained\">\n<div style=\"height:200px\" aria-hidden=\"true\" class=\"wp-block-spacer d-none d-sm-block\"><\/div>\n\n\n\n<h1 class=\"wp-block-heading is-style-display\" id=\"ai-for-science-learning-the-language-of-nature\">AI for Science: Learning the language of nature<\/h1>\n\n\n\n<div style=\"height:200px\" aria-hidden=\"true\" class=\"wp-block-spacer d-none d-sm-block\"><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<article class=\"wp-block-group alignfull mt-0 is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"padding-bottom:0; padding-top:0\" class=\"wp-block-msr-immersive-section alignfull row has-background-gradient has-background-gradient-spectrum-3 wp-block-msr-immersive-section\">\n\t\n\t<div class=\"container\">\n\t\t<div class=\"wp-block-msr-immersive-section__wrapper\">\n\t\t\t<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\t\t<\/div>\n\t<\/div>\n\n\t<\/div>\n\n\n\n<div class=\"wp-block-columns is-style-dark-mode p-4 z-20 container theme-dark is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:16%\"><\/div>\n\n\n\n<div class=\"wp-block-column headings-large is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:68%\">\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer is-style-default d-none d-md-block\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading is-style-default-h3\" id=\"at-microsoft-we-believe-that-the-ability-of-generative-ai-to-learn-the-language-of-humans-is-equally-matched-by-its-ability-to-learn-the-language-of-nature-science-may-be-the-most-important-application-of-ai\">At Microsoft, we believe that the ability of generative AI to learn the language of humans is equally matched by its ability to learn the language of nature.<\/h2>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-cta\"><a data-bi-type=\"button\" class=\"wp-block-button__link wp-element-button\" href=\"#health\">Health<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-cta\"><a data-bi-type=\"button\" class=\"wp-block-button__link wp-element-button\" href=\"#discovery\">Discovery<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-cta\"><a data-bi-type=\"button\" class=\"wp-block-button__link wp-element-button\" href=\"#earth\">Earth<\/a><\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"health\">Health<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"diagnosis-and-treatment\">Diagnosis and treatment<\/h3>\n\n\n\n<p>Generative AI has revolutionized machines&#8217; ability to understand human language and images, particularly in medicine, showing promise for improving patient outcomes and clinician experience.<\/p>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">Virchow<\/h4>\n\n\n\n<p>Microsoft Research, in collaboration with&nbsp;<a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" href=\"https:\/\/paige.ai\/\" target=\"_blank\" rel=\"noopener noreferrer\">Paige<span class=\"sr-only\"> (opens in new tab)<\/span><\/a>, a global leader in clinical AI applications for cancer, is advancing the state-of-the-art in computational foundation models. The first contribution of this collaboration is a model named Virchow. Virchow serves as a significant proof point for foundation models in pathology, as it demonstrates how a single model can be useful in detecting both common and rare cancers, fulfilling the promise of generalizable representations.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Model<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/Virchow\/version\/1\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"Virchow model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Virchow model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Nature MEDICINE Publication<\/span>\n\t\t\t<a href=\"https:\/\/www.nature.com\/articles\/s41591-024-03141-0\" data-bi-cN=\"A foundation model for clinical-grade computational pathology and rare cancers detection\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>A foundation model for clinical-grade computational pathology and rare cancers detection<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Model<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/Virchow2\/version\/2\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"Virchow 2 model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Virchow 2 model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/large-scale-pathology-foundation-models-show-promise-on-a-variety-of-cancer-related-tasks\/\" data-bi-cN=\"Large-scale pathology foundation models show promise on a variety of cancer-related tasks\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Large-scale pathology foundation models show promise on a variety of cancer-related tasks<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">GigaPath<\/h4>\n\n\n\n<p><a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" href=\"https:\/\/www.nature.com\/articles\/s41586-024-07441-w\" target=\"_blank\" rel=\"noopener noreferrer\">GigaPath<span class=\"sr-only\"> (opens in new tab)<\/span><\/a> is a novel vision transformer that attains whole-slide modeling by leveraging dilated self-attention to keep computation tractable. In joint work with Providence Health System and the University of Washington, we have developed&nbsp;Prov-GigaPath, an open-access whole-slide pathology foundation model pretrained on more than one billion 256 X 256 pathology images tiles in more than 170,000 whole slides from real-world data at Providence.&nbsp; All computation was conducted within Providence\u2019s private tenant, approved by Providence Institutional Review Board (IRB).<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"GigaPath: Foundation Model for Digital Pathology | Microsoft Research Forum\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube-nocookie.com\/embed\/eB0SNbTHfl8?feature=oembed&rel=0\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Model<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/Prov-GigaPath\/version\/1\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"Prov-Gigapath model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Prov-Gigapath model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">NATURE PUBLICATION<\/span>\n\t\t\t<a href=\"https:\/\/www.nature.com\/articles\/s41586-024-07441-w\" data-bi-cN=\"A whole-slide foundation model for digital pathology from real-world data\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>A whole-slide foundation model for digital pathology from real-world data<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/gigapath-whole-slide-foundation-model-for-digital-pathology\/\" data-bi-cN=\"GigaPath: Whole-Slide Foundation Model for Digital Pathology\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>GigaPath: Whole-Slide Foundation Model for Digital Pathology<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">BiomedParse<\/h4>\n\n\n\n<p>BiomedParse is a new approach for holistic image analysis by treating object as the first-class citizen. By unifying object recognition, detection, and segmentation into a single framework, BiomedParse allows users to specify what they\u2019re looking for through a simple, natural-language prompt. The result is a more cohesive, intelligent way of analyzing medical images that supports faster, more integrated clinical insights.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Introducing BiomedParse, a groundbreaking foundation model for biomedical image analysis\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube-nocookie.com\/embed\/WUPUypgmB-s?start=5&feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Model<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/MedImageParse\/version\/3\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"MedImageParse model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>MedImageParse model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Nature METHODS Publication<\/span>\n\t\t\t<a href=\"https:\/\/www.nature.com\/articles\/s41592-024-02499-w\" data-bi-cN=\"A foundation model for joint segmentation, detection and recognition of biomedical objects across nine modalities\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>A foundation model for joint segmentation, detection and recognition of biomedical objects across nine modalities<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/biomedparse-a-foundation-model-for-smarter-all-in-one-biomedical-image-analysis\/\" data-bi-cN=\"BiomedParse: A foundation model for smarter, all-in-one biomedical image analysis\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>BiomedParse: A foundation model for smarter, all-in-one biomedical image analysis<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">MAIRA<\/h4>\n\n\n\n<p>Project MAIRA is a project from Microsoft Research that builds innovative, multimodal AI technology to assist radiologists in delivering effective patient care and to empower them in their work. The goal of the project is to leverage rich healthcare data \u2013 including medical domain knowledge, temporal sequences of medical images and corresponding radiology reports, and other clinical context information \u2013 as inputs to developing multimodal frontier models that can be scaled and fine-tuned to many different radiology applications.<\/p>\n\n\n\n<p>By leveraging the <a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" rel=\"noopener noreferrer\" target=\"_blank\" href=\"https:\/\/newsnetwork.mayoclinic.org\/discussion\/mayo-clinic-accelerates-personalized-medicine-through-foundation-models-with-microsoft-research-and-cerebras-systems\/\">Mayo Clinic<span class=\"sr-only\"> (opens in new tab)<\/span><\/a>&#8216;s medical expertise and Microsoft Research\u2019s AI advancements, including the multimodal foundation model MAIRA-2 and the recently published RAD-DINO encoder in Nature Machine Intelligence, we aim to explore and unlock new frontiers in radiology.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">MODEL<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/CxrReportGen\/version\/5\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"CxrReportGen model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>CxrReportGen model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">NATURE MACHINE INTELLIGENCE<\/span>\n\t\t\t<a href=\"https:\/\/www.nature.com\/articles\/s42256-024-00965-w\" data-bi-cN=\"Exploring scalable medical image encoders beyond text supervision\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Exploring scalable medical image encoders beyond text supervision<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">MODEL<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/microsoft-rad-dino\/version\/2\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"microsoft-rad-dino model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>microsoft-rad-dino model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">PROJECT<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/project\/project-maira\/\" data-bi-cN=\"Project MAIRA\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Project MAIRA<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"precision-health\">Precision health<\/h3>\n\n\n\n<p>Precision health focuses on delivering the right treatment to the right patient at the right time. To achieve this, we need to learn from people to treat the patient, ensuring personalized and effective care.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"multidisciplinary-tumor-board\">Multidisciplinary Tumor Board<\/h4>\n\n\n\n<p>Medicine today is imprecise. Cancer is the poster child of this challenge, where often the majority of patients don\u2019t respond to their treatments. Multidisciplinary tumor board is key to advancing precision oncology by assimilating diverse expertise such as radiology, pathology, genomics to identify precision treatment options. However, first-gen tumor boards are operating manually and hard to scale. E.g., when standard of care fails, the last hope lies in clinical trials. But triaging a single patient could take hours. Consequently, only 3% of US cancer patients were able to find a matching trial, whereas 40% of cancer trial failures stem from insufficient enrollment.<\/p>\n\n\n\n<p>GenAI could help scale \u201cuniversal abstraction\u201d to structure all medical data for patients and trials, thus facilitating just-in-time clinical trial matching and democratizing tumor board. <a href=\"https:\/\/www.microsoft.com\/en-us\/research\/group\/real-world-evidence\/\">Microsoft Health Futures<\/a> has pioneered this frontier exploration in close collaboration with large health systems and life sciences companies. A recent <a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" href=\"https:\/\/blog.providence.org\/national-news\/comprehensive-genomic-profiling-leads-to-better-patient-outcomes-new-joint-study-says\" target=\"_blank\" rel=\"noopener noreferrer\">joint study<span class=\"sr-only\"> (opens in new tab)<\/span><\/a> by Providence, Microsoft, and Illumina shows that with AI powering Providence\u2019s tumor board for genomics interpretation and clinical trial matching, Providence researchers were able to identify actionable biomarkers for 67% of late-stage cancer patients in the study, leading to precision treatment for 52% of patients and 47% increase in overall survival. Progress along this direction also opens new possibilities in rapidly assessing how therapies are working in the wild and identifying which subpopulations benefit the most from different interventions, with myriad applications such as clinical trial design and simulation for unlocking population-scale real-world evidence.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"AI for Precision Health\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube-nocookie.com\/embed\/A-aJ96jfhI4?feature=oembed&rel=0\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">BLOG<\/span>\n\t\t\t<a href=\"https:\/\/news.microsoft.com\/source\/features\/digital-transformation\/how-ai-can-help-cancer-patients-receive-personalized-and-precise-treatment-faster\" data-bi-cN=\"How AI can help cancer patients receive personalized and precise treatment faster\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>How AI can help cancer patients receive personalized and precise treatment faster<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">PUBLICATION<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/publication\/scaling-clinical-trial-matching-using-large-language-models-a-case-study-in-oncology\/\" data-bi-cN=\"Scaling Clinical Trial Matching Using Large Language Models: A Case Study in Oncology\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Scaling Clinical Trial Matching Using Large Language Models: A Case Study in Oncology<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">PUBLICATION<\/span>\n\t\t\t<a href=\"https:\/\/ascopubs.org\/doi\/10.1200\/OP.24.00226\" data-bi-cN=\"Widespread Adoption of Precision Anticancer Therapies After Implementation of Pathologist-Directed Comprehensive Genomic Profiling Across a Large US Health System\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Widespread Adoption of Precision Anticancer Therapies After Implementation of Pathologist-Directed Comprehensive Genomic Profiling Across a Large US Health System<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"collaboration-across-industry\">Collaboration across industry<\/h4>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">BLOG<\/span>\n\t\t\t<a href=\"https:\/\/blogs.microsoft.com\/blog\/2023\/08\/22\/microsoft-and-epic-expand-ai-collaboration-to-accelerate-generative-ais-impact-in-healthcare-addressing-the-industrys-most-pressing-needs\/\" data-bi-cN=\"Microsoft and Epic expand AI collaboration to accelerate generative AI\u2019s impact in healthcare, addressing the industry\u2019s most pressing needs\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Microsoft and Epic expand AI collaboration to accelerate generative AI\u2019s impact in healthcare, addressing the industry\u2019s most pressing needs<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Publication<\/span>\n\t\t\t<a href=\"https:\/\/healthinnovation.ucsd.edu\/publications\/ai-generated-draft-replies-integrated-into-health-records-and-physicians-electronic-communication\" data-bi-cN=\"AI-Generated Draft Replies Integrated Into Health Records and Physicians\u2019 Electronic Communication\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>AI-Generated Draft Replies Integrated Into Health Records and Physicians\u2019 Electronic Communication<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Publication<\/span>\n\t\t\t<a href=\"https:\/\/papers.ssrn.com\/sol3\/papers.cfm?abstract_id=4835935\" data-bi-cN=\"Completeness, Correctness and Conciseness of Physician-Written Versus Large Language Model Generated Patient Summaries Integrated in Electronic Health Records\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Completeness, Correctness and Conciseness of Physician-Written Versus Large Language Model Generated Patient Summaries Integrated in Electronic Health Records<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"discovery\">Discovery<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"drug-discovery\">Drug discovery<\/h3>\n\n\n\n<p>AI is showing promise to drastically speed up drug discovery, making previously undruggable targets druggable and vastly improving our efficiency in addressing new diseases, combating drug resistance, and advancing medical knowledge.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">AI<sup>2<\/sup>BMD<\/h4>\n\n\n\n<p>AI<sup>2<\/sup>BMD, short for &#8220;AI-powered <em>ab-initio<\/em> bio-molecular dynamics,&#8221; is a groundbreaking AI framework developed by Microsoft Research AI for Science. It leverages generative AI to simulate protein movements with unprecedented accuracy and speed, revolutionizing the field of drug discovery and protein design.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Nature Publication<\/span>\n\t\t\t<a href=\"https:\/\/www.nature.com\/articles\/s41586-024-08127-z\" data-bi-cN=\"Ab initio characterization of protein molecular dynamics with AI2BMD\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Ab initio characterization of protein molecular dynamics with AI2BMD<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/visnet-a-general-molecular-geometry-modeling-framework-for-predicting-molecular-properties-and-simulating-molecular-dynamics\/\" data-bi-cN=\"ViSNet: A general molecular geometry modeling framework for predicting molecular properties and simulating molecular dynamics\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>ViSNet: A general molecular geometry modeling framework for predicting molecular properties and simulating molecular dynamics<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/from-static-prediction-to-dynamic-characterization-ai2bmd-advances-protein-dynamics-with-ab-initio-accuracy\/\" data-bi-cN=\"From static prediction to dynamic characterization: AI2BMD advances protein dynamics with ab initio accuracy\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>From static prediction to dynamic characterization: AI2BMD advances protein dynamics with ab initio accuracy<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">TamGen<\/h4>\n\n\n\n<p>TamGen, short for &#8220;target-aware molecule generation,&#8221; is a state-of-the-art AI framework designed to accelerate drug design by overcoming the limitations of traditional methods. Developed by Microsoft Research, TamGen leverages advanced AI techniques to predict and generate novel drug molecules with significantly improved binding affinities. <\/p>\n\n\n\n<p>In <a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/ghddi-and-microsoft-research-use-ai-technology-to-achieve-significant-progress-in-discovering-new-drugs-to-treat-global-infectious-diseases\/\">collaboration with GHDDI<\/a>, TamGen has successfully generated small molecule inhibitors for Mycobacterium tuberculosis. Notably, one molecule was 125 times more effective at inhibiting the TB Clp protease compared to the starting molecule. TamGen has also been used to design novel compounds targeting SARS-CoV-2. These compounds feature unique structures compared to existing ones and exhibit an eightfold improvement in bioactivity.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Keynote: The Revolution in Scientific Discovery | Microsoft Research Forum\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube-nocookie.com\/embed\/CJejmZ5Luo4?start=685&feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Model<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/TamGen\/version\/1\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"TamGen model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>TamGen model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Nature COMMUNICATIONS Publication<\/span>\n\t\t\t<a href=\"https:\/\/www.nature.com\/articles\/s41467-024-53632-4\" data-bi-cN=\"TamGen: drug design with target-aware molecule generation through a chemical language model\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>TamGen: drug design with target-aware molecule generation through a chemical language model<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/accelerating-drug-discovery-with-tamgen-a-generative-ai-approach-to-target-aware-molecule-generation\/\" data-bi-cN=\"Accelerating drug discovery with TamGen: A generative AI approach to target-aware molecule generation\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Accelerating drug discovery with TamGen: A generative AI approach to target-aware molecule generation<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"drug-discovery\">Materials discovery<\/h3>\n\n\n\n<p>New technologies are being developed to accelerate materials discovery and design, making it thousands of times faster, paving the way for new materials with desired properties in weeks rather than years.<\/p>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Story<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/story\/ai-meets-materials-discovery\/\" data-bi-cN=\"AI meets materials discovery: The vision behind MatterGen and MatterSim\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>AI meets materials discovery: The vision behind MatterGen and MatterSim<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">MatterGen<\/h4>\n\n\n\n<p>MatterGen is a diffusion model specifically designed for generating materials. Crucially, the model is able to generate materials satisfying a broad range of design requirements, such as target chemistry, symmetry, and properties.&nbsp;<\/p>\n\n\n\n<p>MatterGen reaches state-of-the-art performance in the de-novo generation of novel materials, and outperforms traditional computational methods such as screening.<\/p>\n\n\n\n<p>Additionally, thanks to MatterGen, researchers were for the first time able to experimentally synthesize a novel material proposed by a generative model, observed to have target properties within 20% of design constraints &#8212; quite close from an experimental point of view.<\/p>\n\n\n\n<p>The code is available on <a class=\"msr-external-link glyph-append glyph-append-open-in-new-tab glyph-append-xsmall\" href=\"https:\/\/github.com\/microsoft\/mattergen\" target=\"_blank\" rel=\"noopener noreferrer\">Github<span class=\"sr-only\"> (opens in new tab)<\/span><\/a>, and coming to Azure AI Foundry soon.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"MatterGen: A Generative Model for Materials Design | Microsoft Research Forum\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube-nocookie.com\/embed\/yWXPV3bsC2c?feature=oembed&rel=0\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/mattergen-a-new-paradigm-of-materials-design-with-generative-ai\/\" data-bi-cN=\"MatterGen: A new paradigm of materials design with generative AI\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>MatterGen: A new paradigm of materials design with generative AI<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Nature publication<\/span>\n\t\t\t<a href=\"https:\/\/www.nature.com\/articles\/s41586-025-08628-5\" data-bi-cN=\"A generative model for inorganic materials design\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>A generative model for inorganic materials design<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">MatterSim<\/h4>\n\n\n\n<p>Microsoft Research developed&nbsp;<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/publication\/mattersim-a-deep-learning-atomistic-model-across-elements-temperatures-and-pressures\/\">MatterSim<\/a>, a deep-learning model for accurate and efficient materials simulation and property prediction over a broad range of elements, temperatures, and pressures to enable the&nbsp;<em>in silico<\/em>&nbsp;materials design. MatterSim employs deep learning to understand atomic interactions&nbsp;from the very fundamental principles of quantum mechanics, across a comprehensive spectrum of elements and conditions\u2014from 0 to 5,000 Kelvin (K), and from standard atmospheric pressure to 10,000,000 atmospheres. In our experiment, MatterSim efficiently handles simulations for a variety of materials, including metals, oxides, sulfides, halides, and their various states such as crystals, amorphous solids, and liquids. Additionally, it offers customization options for intricate prediction tasks by incorporating user-provided data.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Model<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/MatterSim\/version\/1\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"MatterSim model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>MatterSim model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/mattersim-a-deep-learning-model-for-materials-under-real-world-conditions\/\" data-bi-cN=\"MatterSim: A deep-learning model for materials under real-world conditions\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>MatterSim: A deep-learning model for materials under real-world conditions<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading is-style-default\" id=\"earth\">Earth<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"atmosphere-prediction\">Atmosphere prediction<\/h3>\n\n\n\n<p>We are advancing Earth system modelling with a single AI model that can predict not only weather but also tropical cyclones, air pollution, and ocean waves.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"virchow\">Aurora<\/h4>\n\n\n\n<p>Aurora is a pioneering AI model developed by Microsoft Research, designed to revolutionise environmental prediction such as weather forecasting. By leveraging deep-learning-based AI similar to large language and vision models, Aurora provides highly accurate and efficient predictions of atmospheric and oceanic conditions, outperforming traditional models in both speed and accuracy.<\/p>\n\n\n\n<p>ECMWF is the European Centre for Medium Range Weather forecasting. They run and are responsible for designing a model called IFS which is widely considered to be the best traditional forecasting system. More recently they have created AIFS, an AI approach. They also evaluate in-house the leading AI models such as Aurora, AIFS, GraphCast, etc. In the course of this, they found that Aurora was outperforming all the others on key metrics.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:29px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Project Aurora: The first large-scale foundation model of the atmosphere | Microsoft Research Forum\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube-nocookie.com\/embed\/Zi4u-JWpY5w?feature=oembed&rel=0\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Model<\/span>\n\t\t\t<a href=\"https:\/\/ai.azure.com\/explore\/models\/Aurora\/version\/1\/registry\/azureml?tid=72f988bf-86f1-41af-91ab-2d7cd011db47\" data-bi-cN=\"Aurora model on Azure AI Foundry\" target=\"_blank\" rel=\"noopener noreferrer\" data-external-link=\"true\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Aurora model on Azure AI Foundry<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-open-in-new-tab\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Blog<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/blog\/introducing-aurora-the-first-large-scale-foundation-model-of-the-atmosphere\/\" data-bi-cN=\"Introducing Aurora: The first large-scale foundation model of the atmosphere\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>Introducing Aurora: The first large-scale foundation model of the atmosphere<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n\n\n\n<div class=\"annotations \" data-bi-aN=\"citation\">\n\t<article class=\"annotations__list card depth-16 bg-body p-4 \">\n\t\t<div class=\"annotations__list-item\">\n\t\t\t\t\t\t<span class=\"annotations__type d-block text-uppercase font-weight-semibold text-neutral-300 small\">Publication<\/span>\n\t\t\t<a href=\"https:\/\/www.microsoft.com\/en-us\/research\/publication\/aurora-a-foundation-model-of-the-atmosphere\/\" data-bi-cN=\"A Foundation Model for the Earth System\" data-external-link=\"false\" data-bi-aN=\"citation\" data-bi-type=\"annotated-link\" class=\"annotations__link font-weight-semibold text-decoration-none\"><span>A Foundation Model for the Earth System<\/span>&nbsp;<span class=\"glyph-in-link glyph-append glyph-append-chevron-right\" aria-hidden=\"true\"><\/span><\/a>\t\t\t\t\t<\/div>\n\t<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:16%\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group theme-dark is-style-default container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<h3 class=\"wp-block-heading is-style-default\" id=\"lightning-talks\">Explore more<\/h3>\n\n\n\n<p>These succinct and informative PDFs were created by researchers for your convenience.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\">\n<p><a href=\"https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/WEF-2025_Leave-Behind_Accelerating-Materials-Design-with-AI.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Accelerating Materials Design with AI<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/WEF-2025_Leave-Behind_Advancing-Protein-Dynamics-Simulation-with-Ab-Initio-Accuracy.pdf\">Advancing Protein Dynamics Simulation with Ab Initio Accuracy<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/WEF-2025_Leave-Behind_AutoGen.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">AutoGen<\/a><\/p>\n\n\n\n<p><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\">\n<p><a href=\"https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/WEF-2025_Leave-Behind_OmniParser-for-Pure-Vision-Based-GUI-Agent.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">OmniParser for Pure Vision-Based GUI Agent<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/WEF-2025_Leave-Behind_Phi-4.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Phi-4<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/WEF-2025_Leave-Behind_Target-Aware-Molecular-Generation.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Target Aware Molecular Generation<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.microsoft.com\/en-us\/research\/wp-content\/uploads\/2025\/01\/WEF-2025_Leave-Behind_TRACE.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">TRACE<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>Generative AI has revolutionized machines&#8217; ability to understand human language and images, particularly in medicine, showing promise for improving patient outcomes and clinician experience. Microsoft Research, in collaboration with&nbsp;Paige (opens in new tab), a global leader in clinical AI applications for cancer, is advancing the state-of-the-art in computational foundation models. The first contribution of this [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":true,"_classifai_error":"","footnotes":""},"research-area":[13556,198583,13553],"msr-locale":[268875],"msr-post-option":[],"class_list":["post-1120251","msr-story","type-msr-story","status-publish","hentry","msr-research-area-artificial-intelligence","msr-research-area-ecology-environment","msr-research-area-medical-health-genomics","msr-locale-en_us"],"related-researchers":[],"related-publications":[],"related-downloads":[],"related-videos":[],"related-projects":[],"related-groups":[],"related-events":[],"related-posts":[],"msr_impact_theme":[],"_links":{"self":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-story\/1120251","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-story"}],"about":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/types\/msr-story"}],"version-history":[{"count":124,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-story\/1120251\/revisions"}],"predecessor-version":[{"id":1131882,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-story\/1120251\/revisions\/1131882"}],"wp:attachment":[{"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/media?parent=1120251"}],"wp:term":[{"taxonomy":"msr-research-area","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/research-area?post=1120251"},{"taxonomy":"msr-locale","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-locale?post=1120251"},{"taxonomy":"msr-post-option","embeddable":true,"href":"https:\/\/www.microsoft.com\/en-us\/research\/wp-json\/wp\/v2\/msr-post-option?post=1120251"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}