Emmy-nominated veteran actor Bryan Cranston (Malcolm in the Middle, Little Miss Sunshine) heads the cast of Breaking Bad, portraying Walter White, a high school chemistry teacher whose life is suddenly transformed by a dire medical diagnosis. Aaron Paul (Big Love) plays Jesse Pinkman, a street-savvy former student who "teaches" Walter a new trade. Anna Gunn (Deadwood) is Walter's pregnant wife Skylar, an enterprising homemaker. Dean Norris (Little Miss Sunshine) is Walter's boisterous and crude brother-in-law Hank who happens to be a federal drug enforcement agent. Betsy Brandt (CSI) plays Walter's sister-in-law Marie, and R.J. Mitte (Hannah Montana, Weeds) is Walter's son, Walter Jr., whose teen angst is further complicated by cerebral palsy.