Understanding SARS-CoV-2

female scientist working in a clean lab pipetting liquid into test tubes

COVID-19 Research

论文与出版物

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- Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations
  
  Md Nasir, Nicole Cook, Daniel Parras, Sumit Mukherjee, Geralyn Miller, Juan M. Lavista Ferres, Katherine Chung-Bridges
  
  Journal of Health Care for the Poor and Underserved | May 2023
  
  Publication 项目
- T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity
  
  Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Boonyaratanakornkit J, Wald A, Selke S, Wener Mh, Morishima C, Greninger Al, Michael Gale, Tien-Ying Hsiang, Lichen Jing, Holbrook Mr, Ian M. Kaplan, Damon H May, H. Jabran Zahid, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S Robins, David M Koelle
  
  JCI Insight | April 2022, 第 7 卷(10)
  
  DOI Preprint Publication 项目项目
- Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection
  
  Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H. Jabran Zahid, Cara L Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I Lorè, Dejan Lazarević, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Andrea Crisanti, Giovanni Tonon
  
  JCI Insight | April 2022, 第 7 卷(10)
  
  DOI Publication 项目
- Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2
  
  Shuyuan Zhang, Qingtai Liang, Xinheng He, Chongchong Zhao, Wenlin Ren, Ziqing Yang, Ziyi Wang, Qiang Ding, Haiteng Deng, Tong Wang, Linqi Zhang, Xinquan Wang
  
  Cell Research | January 2022
  
  Publication
- Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation
  
  Yao Li, Tong Wang, Juanrong Zhang, Bin Shao, Haipeng Gong, Yusong Wang, Xinheng He, Siyuan Liu, Tie-Yan Liu
  
  Advanced Theory and Simulations | September 2021
  
  "Top Downloaded Article" Award, Cover Story
  
  DOI PDF
- Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.
  
  Debra Van Egeren, Alexander Novokhodko, Madison Stoddard, Uyen Tran, Bruce Zetter, Michael Rogers, Bradley L. Pentelute, Jonathan M. Carlson, Mark Hixon, Diane Joseph-McCarthy, Arijit Chakravarty
  
  PLOS ONE | April 2021, 第 16 卷(4): pp. e0250780
  
  DOI Publication Publication Publication Publication Publication Publication Publication 项目
- Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome
  
  Meghana Kshirsagar, Nure Tasnina, Michael D. Ward, Jeffrey N. Law, T. M. Murali, Juan M. Lavista Ferres, Gregory R. Bowman , Judith Klein-Seetharaman
  
  Pacific Symposium on Biocomputing | January 2021
  
  Publication 项目
- A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2
  
  Sean Nolan, Marissa Vignali, Mark Klinger, Jennifer N Dines, Ian M Kaplan, Emily Svejnoha, Tracy Craft, Katie Boland, Mitch Pesesky, Rachel M Gittelman, Thomas M Snyder, Christopher J Gooley, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Luigi D Notarangelo, Jonathan M. Carlson, Joaquin Martinez-Lopez, Harlan S Robins
  
  August 2020
  
  DOI Publication Publication Publication Publication 项目
- Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines
  
  Naveen K Mehta, Roma V Pradhan, Ava P. Soleimany, Kelly D Moynihan, Adrienne M Rothschilds, Noor Momin, Kavya Rakhra, Jordi Mata-Fink, Sangeeta N Bhatia, K Dane Wittrup, Darrell J Irvine
  
  Nature Biomedical Engineering | May 2020, 第 4 卷(6): pp. 636-648
  
  DOI

- Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations
  
  Md Nasir, Nicole Cook, Daniel Parras, Sumit Mukherjee, Geralyn Miller, Juan M. Lavista Ferres, Katherine Chung-Bridges
  
  Journal of Health Care for the Poor and Underserved | May 2023
  
  Publication 项目
- Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation
  
  Yao Li, Tong Wang, Juanrong Zhang, Bin Shao, Haipeng Gong, Yusong Wang, Xinheng He, Siyuan Liu, Tie-Yan Liu
  
  Advanced Theory and Simulations | September 2021
  
  "Top Downloaded Article" Award, Cover Story
  
  DOI PDF
- Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome
  
  Meghana Kshirsagar, Nure Tasnina, Michael D. Ward, Jeffrey N. Law, T. M. Murali, Juan M. Lavista Ferres, Gregory R. Bowman , Judith Klein-Seetharaman
  
  Pacific Symposium on Biocomputing | January 2021
  
  Publication 项目
- Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations
  
  Md Nasir, Nicole Cook, Daniel Parras, Sumit Mukherjee, Geralyn Miller, Juan M. Lavista Ferres, Katherine Chung-Bridges
  
  Journal of Health Care for the Poor and Underserved | May 2023
  
  Publication 项目
- T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity
  
  Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Boonyaratanakornkit J, Wald A, Selke S, Wener Mh, Morishima C, Greninger Al, Michael Gale, Tien-Ying Hsiang, Lichen Jing, Holbrook Mr, Ian M. Kaplan, Damon H May, H. Jabran Zahid, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S Robins, David M Koelle
  
  JCI Insight | April 2022, 第 7 卷(10)
  
  DOI Preprint Publication 项目项目
- Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection
  
  Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H. Jabran Zahid, Cara L Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I Lorè, Dejan Lazarević, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Andrea Crisanti, Giovanni Tonon
  
  JCI Insight | April 2022, 第 7 卷(10)
  
  DOI Publication 项目
- Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2
  
  Shuyuan Zhang, Qingtai Liang, Xinheng He, Chongchong Zhao, Wenlin Ren, Ziqing Yang, Ziyi Wang, Qiang Ding, Haiteng Deng, Tong Wang, Linqi Zhang, Xinquan Wang
  
  Cell Research | January 2022
  
  Publication
- Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation
  
  Yao Li, Tong Wang, Juanrong Zhang, Bin Shao, Haipeng Gong, Yusong Wang, Xinheng He, Siyuan Liu, Tie-Yan Liu
  
  Advanced Theory and Simulations | September 2021
  
  "Top Downloaded Article" Award, Cover Story
  
  DOI PDF
- Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.
  
  Debra Van Egeren, Alexander Novokhodko, Madison Stoddard, Uyen Tran, Bruce Zetter, Michael Rogers, Bradley L. Pentelute, Jonathan M. Carlson, Mark Hixon, Diane Joseph-McCarthy, Arijit Chakravarty
  
  PLOS ONE | April 2021, 第 16 卷(4): pp. e0250780
  
  DOI Publication Publication Publication Publication Publication Publication Publication 项目
- Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome
  
  Meghana Kshirsagar, Nure Tasnina, Michael D. Ward, Jeffrey N. Law, T. M. Murali, Juan M. Lavista Ferres, Gregory R. Bowman , Judith Klein-Seetharaman
  
  Pacific Symposium on Biocomputing | January 2021
  
  Publication 项目
- A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2
  
  Sean Nolan, Marissa Vignali, Mark Klinger, Jennifer N Dines, Ian M Kaplan, Emily Svejnoha, Tracy Craft, Katie Boland, Mitch Pesesky, Rachel M Gittelman, Thomas M Snyder, Christopher J Gooley, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Luigi D Notarangelo, Jonathan M. Carlson, Joaquin Martinez-Lopez, Harlan S Robins
  
  August 2020
  
  DOI Publication Publication Publication Publication 项目
- Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines
  
  Naveen K Mehta, Roma V Pradhan, Ava P. Soleimany, Kelly D Moynihan, Adrienne M Rothschilds, Noor Momin, Kavya Rakhra, Jordi Mata-Fink, Sangeeta N Bhatia, K Dane Wittrup, Darrell J Irvine
  
  Nature Biomedical Engineering | May 2020, 第 4 卷(6): pp. 636-648
  
  DOI

- Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations
  
  Md Nasir, Nicole Cook, Daniel Parras, Sumit Mukherjee, Geralyn Miller, Juan M. Lavista Ferres, Katherine Chung-Bridges
  
  Journal of Health Care for the Poor and Underserved | May 2023
  
  Publication 项目
- T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity
  
  Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Boonyaratanakornkit J, Wald A, Selke S, Wener Mh, Morishima C, Greninger Al, Michael Gale, Tien-Ying Hsiang, Lichen Jing, Holbrook Mr, Ian M. Kaplan, Damon H May, H. Jabran Zahid, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S Robins, David M Koelle
  
  JCI Insight | April 2022, 第 7 卷(10)
  
  DOI Preprint Publication 项目项目
- Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection
  
  Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H. Jabran Zahid, Cara L Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I Lorè, Dejan Lazarević, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Andrea Crisanti, Giovanni Tonon
  
  JCI Insight | April 2022, 第 7 卷(10)
  
  DOI Publication 项目
- Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2
  
  Shuyuan Zhang, Qingtai Liang, Xinheng He, Chongchong Zhao, Wenlin Ren, Ziqing Yang, Ziyi Wang, Qiang Ding, Haiteng Deng, Tong Wang, Linqi Zhang, Xinquan Wang
  
  Cell Research | January 2022
  
  Publication
- Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation
  
  Yao Li, Tong Wang, Juanrong Zhang, Bin Shao, Haipeng Gong, Yusong Wang, Xinheng He, Siyuan Liu, Tie-Yan Liu
  
  Advanced Theory and Simulations | September 2021
  
  "Top Downloaded Article" Award, Cover Story
  
  DOI PDF
- Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.
  
  Debra Van Egeren, Alexander Novokhodko, Madison Stoddard, Uyen Tran, Bruce Zetter, Michael Rogers, Bradley L. Pentelute, Jonathan M. Carlson, Mark Hixon, Diane Joseph-McCarthy, Arijit Chakravarty
  
  PLOS ONE | April 2021, 第 16 卷(4): pp. e0250780
  
  DOI Publication Publication Publication Publication Publication Publication Publication 项目
- Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines
  
  Naveen K Mehta, Roma V Pradhan, Ava P. Soleimany, Kelly D Moynihan, Adrienne M Rothschilds, Noor Momin, Kavya Rakhra, Jordi Mata-Fink, Sangeeta N Bhatia, K Dane Wittrup, Darrell J Irvine
  
  Nature Biomedical Engineering | May 2020, 第 4 卷(6): pp. 636-648
  
  DOI
- Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome
  
  Meghana Kshirsagar, Nure Tasnina, Michael D. Ward, Jeffrey N. Law, T. M. Murali, Juan M. Lavista Ferres, Gregory R. Bowman , Judith Klein-Seetharaman
  
  Pacific Symposium on Biocomputing | January 2021
  
  Publication 项目
- A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2
  
  Sean Nolan, Marissa Vignali, Mark Klinger, Jennifer N Dines, Ian M Kaplan, Emily Svejnoha, Tracy Craft, Katie Boland, Mitch Pesesky, Rachel M Gittelman, Thomas M Snyder, Christopher J Gooley, Simona Semprini, Claudio Cerchione, Massimiliano Mazza, Ottavia M Delmonte, Kerry Dobbs, Gonzalo Carreño-Tarragona, Santiago Barrio, Vittorio Sambri, Giovanni Martinelli, Jason D Goldman, James R Heath, Luigi D Notarangelo, Jonathan M. Carlson, Joaquin Martinez-Lopez, Harlan S Robins
  
  August 2020
  
  DOI Publication Publication Publication Publication 项目

Understanding SARS-CoV-2

论文与出版物

Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2

Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation

Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.

Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines

Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations

Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation

Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome

Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2

Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation

Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.

Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines

Using data science and a health equity lens to identify long-COVID sequelae among medically underserved populations

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2

Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation

Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.

Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines

Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 —human interactome

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2