One year after finding vengeance for his murdered brother, MMA fighter Kurt Sloane finds himself back in Thailand kidnapped and imprisoned there by a powerful gang leader (Christopher Lambert). His only shot at freedom is to win an underground death match against a killer enhanced with state-of the-art drugs. To make it out alive, he seeks training unlike anything he's ever endured, with the help of the legendary Master Durand (Jean-Claude Van Damme) and fellow prisoner Briggs (Mike Tyson).