After a rough breakup, directionless Dave (Alexander England) crashes at his sister’s place and spends his days expanding his young nephew’s questionable vocabulary. When an opportunity arises to chaperone an upcoming school excursion alongside the charming and enigmatic teacher, Miss Caroline (Lupita Nyong’o), Dave jumps at the chance to impress her. What he wasn’t anticipating was Teddy McGiggle (Josh Gad), an obnoxious children’s television personality who shapes the excursion’s activities. What he was expecting even less was a zombie invasion, which unfolds after an experiment at a nearby military base goes awry. Armed only with the resourcefulness of kindergartners, Dave, Miss Caroline, and Teddy must work together to keep the monsters at bay and carve a way out with their guts intact.