Dr Nikki Alexander (Emilia Fox) and the team of forensic pathologists and scientists at the Lyell Centre investigate intriguing new cases: a body falling from the top of a skyscraper, a people trafficking operation, a suspicious death at a festival, a train crash, and corrupt police officers. The cases that end up at the Lyell Centre are rarely straightforward. Initial suspicions are challenged as the evidence mounts and Nikki and the team must work harder than ever to uncover the truth.