"12 Monkeys" will continue the journey of James Cole (Aaron Stanford), a man sent back in time to eradicate the source of a deadly plague, and his partner, brilliant virologist Dr. Cassandra Railly (Amanda Schull). While attempting to untangle an insidious conspiracy that's been spun throughout centuries, the duo embark on a desperate search across time to find the man responsible for the apocalypse - a time traveler who calls himself the Witness. Killing the Witness will save the world, but the journey will come at tremendous personal stakes for the pair.