Boris Karloff stars in Frankenstein, as the screen's most memorable monster, in what many consider to be the greatest horror film ever made. Dr. Frankenstein (Colin Clive) dares to tamper with life and death by creating a human monster (Karloff) out of lifeless body parts. Director James Whale's adaptation of the Mary Shelley novel blended with Karloff's compassionate portrayal of a creature groping for identity makes Frankenstein a masterpiece not only of the genre, but of all time.