MS One is an experimental prison in space where the 500 most dangerous criminals on planet Earth are kept in an artificial sleep. Leading a humanitarian mission, the daughter of the US president, Emilie Warnock (Maggie Grace) arrives on board the station, just as an unprecedentedly violent mutiny breaks out. Emilie and the crew of MS One are taken hostage by the inmates. President Warnock decides to send Agent Snow (Guy Pearce) to MS One with the sole mission of saving Emilie and nobody else...