It's mind over murder as an eccentric neuroscientist with a unique view of the world teams up with the FBI to crack difficult cases. Dr. Daniel Pierce is a neuroscientist and professor recruited by the FBI to help solve complex cases. His intimate knowledge of human behavior and masterful understanding of the mind gives him an extraordinary ability to read people. But his eccentric view of the world and less-than-stellar social skills often interfere with his work. FBI agent Kate Moretti is Pierce's former student and the person responsible for recruiting Daniel to work for the government.