In the year 3001.5, the entire world is under the tyrannical rule of the Maruhage Empire, and their ruler, Tsuru Tsurulina IV (Bald the 4th). His Hair Hunt troop captures innocent bystanders' hair, leaving the people bald and their villages in ruins. Standing against this evil regime is the heroic, but bizarre, rebel, Bobobo-Bo Bo-Bobo, who fights the Hair Hunt Troop with his powerful Hanage Shinken (Fist of the Nose Hair).