Exploit:JS/Blacole.Q is the detection for malicious JavaScript that loads a series of other exploits that are distributed as components of the "Blackhole kit". If the computer runs a vulnerable version of certain software and exploitation is successful, various malware may be downloaded. 

Windows Defender detects and removes this threat.

This trojan can install other malware or unwanted software onto your PC.

It can be installed when you open a spam email attachment.

Find out ways that malware can get on your PC.

Exploit:HTML/IframeRef.BG is a detection for an obfuscated exploit that is embedded within a compromised web page. The exploit creates a malicious IFrame into same web page that, when viewed in a web browser, redirects the browser to another site to possibly execute other malicious code.

Microsoft Defender Antivirus detects and removes this threat.

Qakbot, also known as Quakbot, Qbot, and similar names, has been active since 2007. Qakbot started life as a credential stealer optimized to obtain credentials from banking and other financial services. In 2020 and 2021, Qakbot has been observed to lead to ransomware-as-a-service (RaaS) actors responsible for expedient ransomware and data exfiltration from organizations via purchased access to Qakbot infections.

Qakbot global campaign has been impacting organizations with malicious email deliveries that lead to infection with a renovated Qakbot implant that quickly ascertains system information to determine which organizations are valuable for resale. Qakbot transitions to human re-entry by a motivated operator based on the company or network profile obtained during reconnaissance. The consequences are likely to involve ransomware and data exfiltration as well as increased scope of organizational compromise.

Read these blogs for details:

• Ransomware groups continue to target healthcare, critical services; here’s how to reduce risk
• Hunt for Ransomware
• Human-operated ransomware attacks: A preventable disaster
• Mitigating and eliminating info-stealing Qakbot and Emotet in corporate networks

Worm:iPhoneOS/Ikee.B!script is a script spread by Worm:iPhoneOS/Ikee.B by mobile devices running the iPhone operating system. It installs several programs without the user's consent and also connects to a remote server to upload information and download arbitrary files.