Portrait of Neil Dalchau

Neil Dalchau

Principal Scientist


I am a Principal Scientist in the Biological Computation research group at Microsoft Research Cambridge.

I am interested in how to program computation and decision-making in biological systems. The applications of programmed biology are numerous, including the synthesis of medicines and industrial chemicals, through to the direct treatment of disease. My current research looks at how developmental patterns can be programmed in multicellular or purely chemical systems, taking a Synthetic Biology approach to address fundamental questions of how natural systems develop. I am also interested in how the immune system detects pathogenicity and have contributed several analyses of the antigen presentation (MHC class I) machinery.

My general approach to research is to use mathematical and statistical models to interpret experimental measurements, employing techniques from dynamical systems theory and machine learning. These methodologies have their roots elsewhere in science but are also clearly applicable to biological applications. However, there…